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Diazepam is N-demethylated by CYP3A4 and 2C19 towards the active metabolite N-desmethyldiazepam, and is hydroxylated by CYP3A4 into the Lively metabolite temazepam. N-desmethyldiazepam and temazepam are both of those additional metabolized to oxazepam. Temazepam and oxazepam are largely removed by glucuronidation.Flumazenil, a particular benzodiaze